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If you have hair loss thats bothersome to you, your doctor may prescribe a drug other than Topamax for your condition. Treatment with Topamax can cause a variety of cognitive side effects. I must be the only one with this crazy list, so I thought I would share! Your comment will be reviewed and published at the journal's discretion. 15 min from L. In most cases, side effects from Topamax are temporary. If a child takes Topamax, their doctor will check their growth. Topamax (topiramate) is a prescription drug that's used to treat epilepsy and help prevent migraine headaches. Oh Yes.. Topamax made me stupid and crave non fat milk like it was the best thing in the world. Topamax is also commonly used to prevent migraine headaches in adults. Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. A 39-year-old Caucasian woman developed chronic carbonation dysgeusia after initiation of topiramate following a generalized seizure. Although rare, treatment with Topamax can cause a condition called secondary closed-angle glaucoma. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Learn more. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, problems with sleep, such as sleepiness or, speech problems, such as having trouble thinking of the right words to say, eye side effects, such as sudden vision changes*, severe, negative changes in memory or mood, high level of ammonia in the blood, which can cause, trouble with memory, concentration, or thinking clearly, Not in the United States? Did anyone experience things tasting weird afterwards? Yes, the risk of side effects from Topamax can depend on the strength you take. Video chat with a U.S. board-certified doctor 24/7 in a minute. Examples include hair. Promptly after the initiation of topiramate, the patient lost her ability to taste carbonation in all beverages, including soda, seltzer, and beer. For example, Topamax may cause eye side effects,* such as glaucoma. MNT is the registered trade mark of Healthline Media. Food & smells have been really off too will this adjust this itself out? I am currently almost off Topamax now. These were rare in clinical trials. I do sometimes ask my family to taste something to see if it's "just me" because it's just a weird feeling. HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. Dysgeusia is a medical condition defined as an alteration of the sense of taste.1 Certain medications can lead to dysgeusia through various mechanisms of action involving chemosensory pathways, such as taste, smell, and salivation.2 The majority of cases of taste dysfunction due to medication use cited in the literature involved hypogeusia (partially impaired sense of taste) or the more general dysgeusia.3 Dysgeusia has been reported with use of antibiotics (eg, clindamycin, metronidazole, fluoroquinolones), neurologic medications (eg, central nervous system stimulants, muscle relaxants), and psychotropics (eg, tricyclic antidepressants, anxiolytics, mood stabilizers) as well as antihistamines, antineoplastics, smoking cessation aids, and antifungals, among others.4, Metallic taste following medication administration is a commonly reported medication-induced dysgeusia. "Local trauma" to the tastebuds aka burning your tongue on hot stuff can change your sense of taste. Although rare, Topamax can also cause a glaucoma attack. You may need additional blood tests to monitor your levels while youre taking Topamax. For these reasons, you should not stop taking Topamax unless your doctor tells you its safe to do so. Topamax can cause a high level of acid in the blood. You can register by visiting the program website or calling 888-233-2334. These side effects may be temporary, lasting a few days or weeks. I also just stopped sweating. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Maybe that's not the best description but it definitely tastes weird. And why does orange gatorade taste okay, but orange Powerade taste horrible?? However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. For more information about this side effect, see Side effect specifics below. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. If youve had an allergic reaction to Topamax or any of its ingredients, you should not take Topamax. See photos, tips, similar places specials, and more at Proxi you are totally right. For permissions, please e-mail: journals.permissions@oup.com. Topamax may cause serious side effects. However, whether zinc supplementation may be beneficial for carbonation dysgeusia remains to be established. Tell your doctor if you have lung problems before starting Topamax. For me it stopped controlling my headaches after about 9 months. Najafizade et al24 demonstrated that zinc supplementation increased perception of all sweet, sour, bitter, and salty tastes among patients with head or neck cancer undergoing radiotherapy. UPDATE: OMFG! You may have changes in your sense of taste as a result of taking Topamax. What I learned and what the Dr. Reccomended was take B vitamins every day. However, you should not stop taking Topamax unless your doctor recommends this. You could also download a reminder app on your phone. If you have more questions about liver problems with Topamax, your doctor can help. Be sure to talk with your doctor about your health history before you take Topamax. Examples include hair loss and eye problems. 6. Lowered BMD could mean your bones are weakened. All rights reserved. During a crisis, people who are hard of hearing can use their preferred relay service or dial 711 then 988. High blood levels of ammonia (a waste product made by your body), which may cause swelling in your brain. Theyll recommend whether you should stop taking the drug. Topamax (topiramate) tablets, for oral use; Topamax (topiramate capsules) sprinkle capsules, for oral use. Treatment involves addressing the underlying cause of dysgeusia. Its possible to have hair loss while taking Topamax. If your doctor confirms you had a mild allergic reaction to Topamax, theyll decide whether you should continue taking the drug. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have thoughts of harming yourself while taking Topamax, call 911 or your local emergency number right away. Your doctor can help determine whether treatment with Topamax is safe for you. Highlights of prescribing informationTopamax, A method for estimating the probability of adverse drug reactions, Topiramate in the treatment of partial and generalized epilepsy, Topiramate as an inhibitor of carbonic anhydrase isoenzymes, Carbonic anhydraseIV mediates the fizz of carbonated beverages, Side effects of acetazolamide: the champagne blues, Altered taste secondary to acetazolamide therapy, Energy and nutrient consumption of patients with dysgeusia, The effect of different methods of drinking a carbonated beverage on the pH of dental plaque: an in vivo study, Preventive effects of zinc sulfate on taste alterations in patients under irradiation for head and neck cancers: a randomized placebo-controlled trial. Symptoms can be mild or serious and can include: If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. These problems include chronic obstructive pulmonary disease (COPD). Children are less likely than adults to experience the following side effects from Topamax: Also, children taking Topamax may experience decreased bone mineral density (BMD). I take 500mcg a day. If youd like to notify the FDA about a side effect youve had with Topamax, visit MedWatch. Topiramate is used alone or with other medications to prevent and control seizures ( epilepsy ). At the time of writing, 12 months had passed since topiramate initiation and the patients sense of carbonation had not returned to normal. For me (i was eventually on 250 mg for migraines) every time I increased my dose I had those symptoms for about 2 or 3 days and then would subside until my next increase.I did discuss the anxiety with my Dr. and he prescribed xanax which helped a lot. Is the ketogenic diet right for autoimmune conditions? It is just as hard coming off this drug as it is going on it. She was also experiencing mild hand and feet paresthesia, which are commonly reported adverse effects of the medication.14 Bloodwork performed 10 months after topiramate initiation indicated that all values were within normal limits, with the exception of a low alkaline phosphatase (ALP) level (38 U/L [reference range, 50-136 U/L] and low creatinine concentration (0.7 mg/dL [reference range, 0.8-1.3 mg/dL]; neither low value was deemed concerning. In fact, carbonic anhydrase 4 may function as the principle CO2 taste sensor for the human body. I had a few side effects to start with like tingling fingers, face and heels but that was bearable, and of course the weight loss which is an added bonus, but . Her last generalized seizure had occurred 23 years prior, and her last known partial seizure activity had occurred 15 years prior. Its important to note that the dosage of Topamax is higher for seizures than for migraine headache prevention. In fact, metallic taste is a reported adverse effect of over 300 medications.5 Medications with sulfhydryl groups, such as acetylcholinesterase inhibitors and antithyroid agents (propylthiouracil and methimazole), can cause metallic tastes. In clinical trials, reduced growth was more commonly seen among children ages 6 to 9 years. chronic obstructive pulmonary disease (COPD), accessdata.fda.gov/drugsatfda_docs/label/2021/020505s063,020844s054lbl.pdf, Getting Relief from Migraines: Preventive and Acute Treatments, Seizure First Aid: How to Respond When Someone Has an Episode. Here we describe a case of carbonation dysgeusia potentially related to the initiation and continued use of topiramate following a generalized seizure. I'm new to this pill and started taking it on Monday and have already been seeing side effects (lethargy, confusion, slowness) etc which I expected to happen but I started to notice today that carbonated drinks didn't feel fizzy and felt flat on my tongue and tasted different? dry mouth. Topiramate is used for migraine headache prophylaxis in adults and for adjunctive or monotherapy treatment of partial onset seizures, primary generalized tonic-clonic seizures, and seizures related to Lennox-Gastaut syndrome.14 Its antiepileptic properties may be due to several mechanisms of action; topiramate blocks voltage-dependent sodium and calcium channels in addition to inhibiting excitatory glutamate pathways and potentiating inhibitory aminobutyric acid effects.16 Topiramate also inhibits carbonic anhydrase activity.17 Its mechanisms of action may underlie both its clinical utility as well as its unique adverse effects. 1 more week and I'm finished. If you or someone you know is in crisis and considering suicide or self-harm, please seek support: If youre calling on behalf of someone else, stay with them until help arrives. I just started on Topamax (topiramate), (topiramate) but I've gotten a headache today that doesn't seem to want to go away. Like other drugs, Topamax can cause side effects. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. And do not stop using Topamax unless your doctor recommends it. * This side effect can affect your ability to drive or safely operate machinery. Your doctor can talk with you about the risks and benefits of taking Topamax while breastfeeding. If I have side effects from Topamax, will I need to take a lower dose of the drug? If you have glaucoma, Topamax may not be safe for you to take. Forgetting stuff at the grocery store, where I put my keys, stuff like that. You should always consult your doctor or another healthcare professional before taking any medication. However, the drug can also cause some serious side effects which may require treatment. a stuffy and runny nose. Just an FYI I didn't start to lose my hair until I was on 150mg of the topamax. The uses and impacts of topiramate are vast and can drastically vary by person. Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. What are the serious side effects of Topamax? This may make some side effects more likely. 2023 Healthline Media LLC. These conditions may raise the acid level in your blood. Know someone with epilepsy? Carbonation dysgeusia as a result of topiramate therapy is not well identified in the literature but has been reported by patients in online chat forums.7 More frequently identified in the literature as causing carbonation taste alterations is acetazolamide, a carbonic anhydrase inhibitor. Find out whats causing frothy saliva and how to, Melatonin can be a successful natural sleep aid. I also lost all interest in food, no apetite, had no energy to cook it, and just threw it up if I did eat it. Topamax is an appetite suppressant and studies confirm Topamax does cause significant weight loss. Topamax information for Healthcare Professionals. I've been on Topamax for two months and I still can't stand to smell food, or taste what I eat or drink. Available for Android and iOS devices. Oh, yeah. Case assessment using the adverse drug reaction probability scale of Naranjo et al15 indicated a probable relationship between topiramate use and carbonation-perception loss (ie, a score of 5). Before taking Topamax, tell your doctor if you have diarrhea thats frequent or hard to manage. So I've been on Topamax since around September and I've only lost like 3 lbs unfortunately lol. However, missing doses may cause you to have symptoms of the condition youre using Topamax to treat. Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. If you have bone problems before starting Topamax treatment, you may have a higher risk of bone problems related to high acid levels. But the following side effects may be more likely to happen in children: Also, when Topamax is taken by children, it may cause reduced bone mineral density (BMD). If you have questions about side effects from Topamax, talk with your doctor or pharmacist. A 39-year-old Caucasian woman with epilepsy had a generalized seizure after 12 years without use of antiepileptic medication. Taste . Before taking Topamax, tell your doctor if you have kidney problems. Although the sense of carbonation when drinking with a straw was not as intense as it was prior to topiramate initiation, she noticed considerable improvement; the straw enhanced the carbonation taste sensation enough to make some carbonated beverages palatable.. It has been FDA-approved since 1996 for the treatment of epilepsy in both children and adults. Following a ketogenic (keto) diet can increase acid levels in your blood. I know topamax (topiramate) for migraine also works as appetite suppressant, but what is the chemical reason? Which can be very dangerous and just plain weird. The suggestion of drinking carbonated beverages through a straw to mitigate carbonation dysgeusia is an interesting recommendation. Ohhhh Topamax. However, you should not stop taking Topamax unless your doctor recommends this. Below we provide information about Topamax and pregnancy and breastfeeding. Treat epilepsy * in. Bone problems. People with the condition feel that all foods taste sour, sweet, bitter or metallic. For me it stopped controlling my headaches after about 9 months. Topamax (topiramate) tablets, for oral use; Topamax (topiramate capsules) sprinkle capsules, for oral use. The topiramate level was not rechecked after the first determination 17 days after topiramate initiation. It can cause side effects that range from mild to serious. Our website services, content, and products are for informational purposes only. Kidney problems may increase the level of acid in your blood. Topamax is known to pass into breast milk. This drug may not be the right treatment for you if you have certain medical conditions or other factors that affect your health. If you have any eye problems while taking Topamax, tell your doctor right away. Thank you for submitting a comment on this article. But these side effects werent common in studies of the drug. Mad that none of the doctors picked up on it. Taste buds are each made up of taste receptor cells that bind to small molecules related to flavor. Summary. Breathing or lung problems. swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe, what dose of drug you were taking when you had the side effect, how soon after starting that dose you had the side effect, what your symptoms were from the side effect, what other medications you were also taking, any other information you feel is important. Over the course of months she tried multiple carbonated beverages, including soda, seltzer, beer, champagne, and energy drinks. It's not common but it can happen and did to me. (2022). Topamax may also affect weight and height in children taking the drug. It all tastes weird & just bad, like an awful stinging, metallic taste on my tongue. Topiramate is a second-generation antiepileptic drug that is used in the treatment of seizure disorders and migraine headaches. You can take Topamax with food or without it. Cookie Notice Your doctor can help determine whether treatment with Topamax is safe for you if you have liver problems. I recently started taking topamax (topiramate) , soda and chocolate taste funny . Treatment with Topamax for migraine prevention is taken daily and is usually started slowly at lower doses. What are the more common side effects of Topamax? Or they may recommend switching from Topamax to a different treatment for your condition. Metformin has also been associated with metallic taste, which tends to resolve after a few months of metformin use. This type of diet may raise the level of acid in your blood. For a general overview of Topamax, including details about its uses, see this article. Luykx J, Mason M, Ferrari MD, Carpay J. Donegan S, Dixon P, Hemming K, Tudur-Smith S, Marson A. Naranjo CA, Busto U, Sellers EM et al. Taking Topamax while pregnant can cause harm to the fetus. Some side effects can cause long-term effects if they arent treated, such as increased pressure in your eye. This helps researchers understand the risks of using Topamax during pregnancy, which can help others make decisions about their treatment. How long does Topamax stay in your system. If youre concerned about weight changes after you start or stop Topamax, talk with your doctor.

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